Andre Johnson is starting over.

After thriving for 12 seasons in Houston, he’s working with a new quarterback and learning a new playbook. And now he’s ready to head home Saturday after finishing his first training camp on a college campus.

On Sunday at Philadelphia, Johnson’s transformation will be complete when he dons a Colts jersey for his first game.

“I don’t really bring much attention to that,” he said. “I just try to treat it as football — with a different team.”

To Johnson, it’s just business.

The seven-time Pro Bowler joined Indianapolis as the replacement for an old college friend, Reggie Wayne.

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